Medication in the Calibrate Program: Introducing Wegovy™
(Semaglutide 2.4)

Treatment within the Calibrate Program: Introducing Wegovy™ (Semaglutide 2.4)

By Isabelle Kenyon, Founder & CEO, and Kim Boyd, MD, Chief Medical Officer

At Calibrate, we all know that weight reduction shouldn’t be about willpower, however relatively our biology. Due to this, our aim is to deliver you a science-based program to enhance your metabolic well being and unlock long-term, sustainable weight reduction. One cornerstone of that is FDA-approved prescription remedy that works together with your biology. 

Calibrate medical doctors prescribe a category of metabolic drugs that mimic the impact of glucagon-like peptides-1s. GLP-1s are highly effective hormones made by your intestine that ship indicators to your mind to control your metabolic perform, aid you really feel full, and reduce your urge for food. Analysis means that individuals who maintain onto extra weight expertise reductions in GLP-1 signaling. 

Completely different doses of semaglutide have been FDA-approved since 2017 (Ozempic®) and 2019 (Rybelsus®). Now, following its recent Food and Drug Administration’s (FDA) approval, we’re excited to announce that we’re including a brand new greater dose of semaglutide to our program—known as Wegovy™. 

Results of GLP-1s within the physique.


Semaglutide has been researched for greater than a decade and is understood to be each efficient and secure. However the brand new dose demonstrates much more metabolic well being advantages and weight reduction than earlier doses. 

As a part of its remaining FDA approval, Novo Nordisk, the pharmaceutical firm that developed semaglutide, has launched a multi-year, four-part trial on Wegovy™, known as the STEP (Semaglutide Treatment Effect in People with obesity) trials. Roughly 4,500 adults with weight problems or who had been chubby participated. 

Every of the 4 research targeted on weight as the first endpoint and demonstrated weight reduction from 15-20% over the course of a yr, with a specific deal with the sustainability of that weight reduction over the longer-term. 

All the trials had been revealed individually, and you may overview them right here or talk about them together with your Calibrate medical staff: STEP 1 in New England Journal of Medicine, STEP 2 in The Lancet, STEP 3 in The Journal of the American Medical Association, STEP 4 in The Journal of the American Medical Association.



All Calibrate members will probably be thought of, as clinically acceptable, for Wegovy™. Calibrate medical doctors at all times overview your medical historical past and metabolic markers to ensure GLP-1 remedy is best for you and to make sure you’re receiving the most effective and handiest GLP-1 for you. Our staff additionally works intently together with your industrial insurance coverage so you may obtain your GLP-1 remedy for a copay of $25/month or much less.  

It’s additionally price noting that Calibrate members have averaged higher metabolic well being enchancment and extra weight reduction than the members of the medical trials of the GLP-1s we use, and that analysis has proven that behavior change is crucial to sustaining weight reduction over time. In different phrases, whereas GLP-1s are highly effective, our program and your weight reduction are about far more than the remedy alone.

No matter which GLP-1 you’re prescribed, our aim is that every one Calibrate members will sustainably enhance metabolic markers and lose 10% or extra of their physique weight when each a part of our program is built-in into their lives.


We’re dedicated to bringing the newest research-based, FDA-approved metabolic science to our members and consider that the long run is vivid. Past Wegovy™, there are a number of different new, highly-effective GLP-1s and GLP-1 mixture drugs approaching FDA approval. 

In partnership with our Medical Advisory Board, we’re intently following the progress of those drugs, in addition to rising analysis on different molecules that influence the intestine mind axis and play a task in regulating our metabolic well being. 

With every new scientific breakthrough, we come nearer to reaching our mission to alter the way in which the world treats weight by giving each Calibrate member the chance to take management of their metabolic well being.

When you have extra questions on our One-Yr Metabolic Reset program, attain out to

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Treatment within the Calibrate Program: Introducing Wegovy™
(Semaglutide 2.4)

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